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Despite the differences among theories, current research agrees that epigenetic alterations and hormonal dysregulation, leading to inflammation, are central features of endometriosis (12), with reactive oxygen species (ROS) serving a key role in this inflammatory response (4)
doi: 10.2174/156720211798120972 259
For image processing, raw data underwent spatial down sampling (2 binning) and we corrected motion artifacts using Inscopix Data Processing Software (v1.3.1) through the following sequential steps: (i) defective pixel correction and file size reduction during preprocessing
Under quiescent conditions, cytosolic Nrf2 directly binds to Kelch-like ECH-associated protein 1 (Keap1), a substrate adapter protein for the Cul3E3ligase complex, resulting in rapid degradation of Nrf2 (Ulasov et al., 2022)