This monomeric oxidized form is generated by an intrasubunit disulfide bond between the Cys-47 and Cys-101 residues [24], [25] and is distinguishable from the reduced form because of its higher electrophoretic mobility
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Its most extensively studied molecular property is G-actin sequestration : Tb4 binds monomeric actin and participates in the regulation of the actin cytoskeleton, the protein scaffold that drives cell shape and, critically, cell migration