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Always review complete prescribing information and discuss potential risks with your healthcare provider before starting any treatment

A small subset of "sentinel" participants is dosed first, before the rest of the cohort, as an additional safeguard

In patients who develop unexplained lethargy and vomiting or changes in mental status, hyperammonemic encephalopathy should be considered and an ammonia level should be measured

- Interpret ffm and fat free mass as lean body mass when the note is using them as equivalent body-composition metrics

Generic manufacturers typically file applications 6 to 12 months before patent expiration, with approval taking another 12 to 18 months