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Oleanolic acid-derived bardoxolone methyl, a dual activator of Nrf2 and inhibitor of the NF-B pathway, entered clinical trials for the treatment of diabetic nephropathy and chronic kidney disease (de Zeeuw et al
Supplement Facts: Serving Size: 1-2 capsules Servings Per Container: 60-30 Amount Per Serving: Conjugated linoleic acid (CLA) 80%: 1000 mg (of which CLA 800 mg) Green tea extract: 400 mg (of which EGCG 132 mg) L-carnitine: 200 mg *RI - Reference Intake Ingredients: 37% conjugated linoleic acid CLA, 14.8% green tea extract, soybean oil , 7.4% L-carnitine, capsule (gelatine, glycerin, water, colour: E172) Recommended Use: Take 1-2 capsules two times daily after breakfast and approximately 30 minutes before physical activity
Continued research remains necessary to further characterize the biological significance of this peptide
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