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First, when you take a pill, it has to be digested and metabolized through the liver or kidney through what is called the first-pass effect

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6 B12 loading jabs over 2 weeks followed by a jab every 2 or 3 months 2) UK recommended treatment for B12 deficiency WITH neuro symptoms is A B12 loading jab every other day for as long as symptoms continue to get better then a jab every 2 months

In our trial, vitamin B-12supplemented mothers had higher blood vitamin B-12 concentrations during pregnancy but not significantly lower MMA or tHcy blood concentrations