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Smaller dose-finding work (Falutz et al., PMID 22298602 review) established that lower doses produced proportionally lower visceral-fat reduction and lower IGF-1 elevation

Otras hormonas, ahora denominadas incretinas, el GLP-1 y el pptido inhibidor gstrico o pptido insulinotrpico dependiente de glucosa ( glucose-dependent insulinotropic peptide

As in the previous recommendations by the ADA and EASD (73, 74), life-style intervention (with patient education and motivation, increase of physical activity, and healthy eating) is still in the beginning and center of therapy, followed by pharmacological therapy with metformin (7074)

The long-term safety profile remains a question mark, and pharmacy availability is years away

The cost of not treating long enough Weight regain carries its own financial burden