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By target indication, the type 2 diabetes segment held a major market share of approximately 55% in 2025

10% require participation in a lifestyle or weight loss program while using the medication

If you miss your weekly 2.4 mg dose by a day or two, take it as soon as you remember and resume your normal schedule the following week

spreading it out potentially improves tolerance

The most common side effects of Zepbound in clinical trials when compared to placebo include: Nausea Diarrhea Vomiting Indigestion Constipation Some other possible side effects of Zepbound include: Burping Fatigue Stomach pain Hair loss Injection site reactions Dizziness Zepbound may also cause more serious side effects including: Serious allergic reactions, including: hives, swelling of your throat and tongue, trouble breathing Increased risk of thyroid cancer or thyroid tumors Pancreatitis (inflammation of your pancreas) Kidney damage including kidney failure Gallbladder problems including gallstones Hypoglycemia (dangerously low blood sugar) Vision changes in people with type 2 diabetes (diabetic retinopathy) Worsening depression or suicidal thoughts Disclaimer: These are not all of the possible adverse events of Zepbound