The practical implication is that if you tolerated semaglutide or tirzepatide well, you will likely tolerate retatrutide at equivalent GLP-1 activity levels
A randomized, sham-controlled trial of intraductal meibomian gland probing with or without topical antibiotic/steroid for obstructive meibomian gland dysfunction
Most chronic diseases are inflammatory in nature, and the systemic anti-inflammatory properties of GLP-1, combined with the abundance of GLP-1 receptors throughout the body, open the door to addressing cardiovascular disease, kidney disease, sleep apnea, osteoarthritis, and more, making the wider potential for this range of therapeutics very exciting
Its mechanism is broader, its attention curve is steeper, and its data has made a much louder impact
Hyperproliferative cutaneous events, including cutaneous SCC, were considered to be related to paradoxical activation of the MAPK pathway and occurred less frequently with the addition of the MEK inhibitor