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To verify the role of targeting ligands in the cellular uptake process, alanine and GSH were added at high concentrations during the uptake assay of the targeted nanocarriers

Glutathione plays a crucial role in the detoxification process by binding to toxins and removing them from the body

Therefore, Fn3k is a potentially actionable drug target and is under active investigation

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They call for larger, longer-term clinical studies to better understand whether L-carnitine can meaningfully influence inflammatory signaling pathways and to determine its full therapeutic role in managing rheumatoid arthritis