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Key Points Compounded semaglutide uses the same active ingredient as Ozempic and Wegovy, but is made by specialized pharmacies The FDA banned compounded versions in May 2025 after declaring the Ozempic shortage resolved, with rare exceptions only for specific medical needs Safety risks include inconsistent dosing between batches, potential contamination, and a lack of robust clinical trial data Insurance rarely covers compounded versions, while brand-name medications offer manufacturer savings programs that reduce monthly costs In early 2022, millions of people were unable to find their prescribed Ozempic and Wegovy medications anywhere