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For any multi-dose use, bacteriostatic (BAC) water is essential, as its preservative prevents bacterial growth in the vial over time

CTK solution (0.25% trypsin + 1 mg/mL collagenase IV + 1 mM CaCl 2 + 20% KSR in DPBS ()) was prepared with trypsin ((2.5%), no phenol red, Thermo Fisher Scientific Inc.), collagenase (type IV, powder, Thermo Fisher Scientific Inc.), calcium chloride dihydrate (Fujifilm Wako Pure Chemical Corporation), Knock Out TM Serum Replacement (KSR, Thermo Fisher Scientific Inc.)

It is usually important for people with kidney or internal organ problem

It also suppresses NF-kB p65 and p38 MAPK signaling, two pathways that are hyperactivated in psoriasis