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These enzymes not only maintain basal metabolic flux through their catalytic activity but also participate in epigenetic regulation, transcription factor activation, redox homeostasis, and the modulation of cell death pathways, thereby acting as upstream drivers of mitochondrial metabolic reprogramming [95]

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L-Carnitin untersttzt dabei, die Fettsuren in die Mitochondrien zu transportieren

Furthermore, there have been significant advances in determining the role of both the innate immune system and genetic factors that might predispose individuals to APAP-mediated toxicity