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These agents mimic the action of endogenous GLP-1, an incretin hormone released from intestinal L-cells in response to nutrient intake

Understanding the differences between available medications, their mechanisms of action, and individual tolerance factors helps patients and healthcare providers select the most appropriate treatment

One final consideration is that as more states establish upper payment limit (UPL) setting authority either for prescription drug affordability boards or other similar entities, it becomes increasingly possible that GLP-1s could be subject to review and UPLs across various states

Visualization of epithelial-mesenchymal transition in an inflammatory microenvironmentcolorectal cancer network

Najar Nobari, M