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Research status Not FDA-approved

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Recent studies also indicate that CAFs modulate tumor metabolic support by the transfer of nutrients and metabolic symbiosis, thereby contributing to the maintenance of cancer cell growth (121)

Mol Endocrinol 11(13):19241933 Hastie PM, Haresign W (2006) Expression of mRNAs encoding insulin-like growth factor (IGF) ligands, IGF receptors and IGF binding proteins during follicular growth and atresia in the ovine ovary throughout the oestrous cycle

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