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Detailed Mechanism of Action Phentermine works through multiple pathways to promote weight loss: Neurotransmitter Modulation : It stimulates the release of norepinephrine in the hypothalamus, which helps regulate appetite control centers in the brain

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For example, ionotropic glutamate receptors represent ligand-gated calcium channels while GABA receptors trigger calcium influx via voltage-gated calcium channels [94]

Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: relevance to schizophrenia