Lean PCOS : the metabolic rationale is weaker, and other approaches are prioritised
Juul is world renowned for his pioneering research on gut hormones, and is actually one of the scientists who co-discovered GLP-1 in the 80s
( Epub 2025 Apr 30 PMID: 40318682 ) Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A, SURMOUNT-1 Investigators (2022) Tirzepatide once weekly for the treatment of obesity
Research in animal models using both peptides is anticipated to reveal enhanced benefits without dramatically increasing adverse effects
Dopaminergic neurons locate principally in the ventral tegmental area (VTA), the substantia nigra pars compact (SNc) of the midbrain, and the arcuate nucleus of hypothalamus