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The SELECT trial enrolled 17,604 patients with a mean body mass index (BMI) of 33.3 and preexisting cardiovascular disease (prior heart attack, stroke, or peripheral artery disease) but no diabetes

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273 Furthermore, a study using the anterior cruciate ligament transection (ACLT) rat model further confirmed that subcutaneous injection of liraglutide at 50 g/kg/day, whether for 3 weeks or 6 weeks, could reduce OARSI scores, highlighting the potential of liraglutide in treating joint degeneration

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