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In addition, consistent with our current knowledge of intestinal FXR signaling and our hypothesis, the GLP-1 production was increased, while the glucose metabolism was improved in MMI-treated IFXRKO mice as compared to MMI-treated Floxed mice (Fig

The decline in skeletal muscle mass is closely linked to andropause and menopause, which are marked by reduced sex steroid and growth hormone levels [17, 18]

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