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According to clinical trial data for semaglutide: nausea (up to 44% of patients) and diarrhoea (~30%) are the top complaints , followed by vomiting (~24%), constipation, and general stomach discomfort

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Most people start at 2.5 mg for 4 weeks, then increase to 5 mg, then 7.5 mg, then 10 mg, with potential further increases to 12.5 mg and 15 mg

(Skip ahead to tips on lowering your tirzepatide costs.) Important: Insurance does not usually cover compounded tirzepatide

Semaglutide delays gastric emptying, or the process by which food empties out of your stomach into the small intestine