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The NHS includes weight gain as a possible menopause symptom: Weight gain in menopause (NHS)

Farzaei M, Zobeiri M, Parvizi F, El-Senduny F, Marmouzi I, Coy-Barrera E, Naseri R, Nabavi S, Rahimi R, Abdollahi M (2018) Curcumin in liver diseases: a systematic review of the cellular mechanisms of oxidative stress and clinical perspective

Typically, 23 months of consistent use is needed for noticeable changes, depending on dosage, skin type, and metabolism

GF mice display disrupted BBB integrity, characterized by reduced tight junction protein expression and increased permeability, underscoring the essential role of the microbiota in barrier homeostasis [231]