At The Institute for Weight Management, we use GLP-1 injections as part of a comprehensive weight loss plan to help patients better control their food intake
Here are some common reasons a provider may recommend pairing B12 with tirzepatide: Patient is at a higher risk for vitamin B12 deficiency Patient has confirmed low B12 levels and is low in energy To monitor nutritional health during long-term GLP-1 treatment Important note: Vitamin B12 is not a weight-loss medication, nor does it enhance tirzepatides effects
However, the permanence of this weight loss can depend on long-term follow-up and lifestyle modifications
ClinicalTrials.gov No registered or completed human clinical trial for SLU-PP-332 as of June 2026
9,12,17 Remaining questions include the longer-term efficacy and safety of these agents, as well as their efficacy and safety in additional populations, including geriatric patients, pediatric patients, or overweight but non-obese adults without comorbidities