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Although less than a decade has passed since the first GIP(3-30)NH 2 injection in humans, substantial research has already contributed to the confirmation of GIP signaling pathways, genetic variations, as well as preclinical and clinical outcomes of GIP receptor targeting compounds (124)

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Individual outcomes depend heavily on baseline BMI, age, metabolic health markers, and adherence to prescribed dosing

Although substantial efforts have been made to improve clinical outcomes, existing therapeutic strategies demonstrate limited efficacy

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