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However, subsequently, in a trial that I led of nearly 19,000 participants in 42 countries around the world, there was a significant excess of depression, neuropsychiatric side-effects and suicidal ideation which spelled the end of that drugs life

Meanwhile, insulin resistance (IR) not only co-occurs with depressive symptoms but also contributes to poor antidepressant treatment response and is closely associated with metabolic subtype depressionrepresenting a shared biological mechanism underlying both depression and T2DM (Khawagi et al., 2024

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Are the compounded versions of these injections FDA-approved