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They may help lower cardiovascular risk Both medications provide benefits for heart health in people with type 2 diabetes

The medication protocol is not prescribed for those with a BMI under 30, active eating disorders, gallbladder disease, history of substance abuse, very recent bariatric surgery, pancreatitis, thyroid cancer, or other specific exclusions

26 In the SURMOUNT-2 trial involving adults with type 2 diabetes, average weight loss over 72 weeks was approximately 13.4% (10 mg) and 15.7% (15 mg), compared to 3.3% for placebo

Most patients experience side effects within the first week of starting treatment or following a dose increase, with gastrointestinal symptoms such as nausea being particularly common

Serious side effects from Rybelsus are not common, but they can happen