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However, exceeding recommended doses significantly increases the risk of severe gastrointestinal symptoms, dehydration, electrolyte disturbances, and potentially life-threatening complications

Other confirmatory secondary outcomes controlled for multiplicity included patients achieving at least a 10% reduction (in 3 studies), a 15% reduction (in 3 studies), and a 20% reduction (in 1 study) in body weight by week 68, and change from baseline to week 68 in the physical function component of the Short Form (36) Health Survey (SF-36) version 2 acute (in 4 studies)

Gradually increase your pace and duration as your stamina improves

Support from family, friends, or a community group can make a big difference

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