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In the study, when mice were fed on high-fat, high-sugar diets, those supplemented with 10 per cent beta-glucan showed significantly less weight gain, reduced fat mass, higher retention of lean mass, improved insulin sensitivity and better blood sugar levels

HIF-1 is a heterodimeric transcriptional factor composed of two subunits, HIF-1 and HIF-1 17

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As an example, polysaccharides were found to significantly lower serum transaminase levels in mice suffering from immunological liver injury induced by concanavalin A, inhibit the release of a large number of inflammatory factors, and alleviate the effects of oxidative stress response by regulating Nrf2/antioxidant response element and TLR4/NF-B signaling pathway (108)