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Thus, GPX4 inactivation blocks the CREB/EP300/GPX4 axis, and these findings reveal that SLC7A11 or GPX4 inhibition sensitizes LUAD cells to ferroptosis, providing a potential therapeutic approach for this currently incurable disease (Wang Z
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doi:10.1038/clpt.2010.184 Lyssenko V, Lupi R, Marchetti P et al (2007) Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
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