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Pour prserver durablement ce rsultat, le patient devra maintenir un poids stable et conserver une bonne hygine de vie sur la base dune activit sportive rgulire et dune alimentation quilibre

Treatment with oral semaglutide improves the fasting lipid level profile, as exploratory analysis resulted in a statistically superior reduction in total cholesterol [35, 38, 42], low-density lipoprotein (LDL) [35, 42], triacylglycerols (TAGs) [35, 38, 39], and very-low-density lipoprotein (VLDL) compared to the effects of placebo [38]

in retatrutide, this effect is thought to be offset by the concurrent GLP-1 and GIP receptor agonism, which promote insulin secretion

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L cells express the surface receptor TGR5, and TGR5 agonists such as 6-ethyl-23(S)-methylcholic acid (EMCA, INT-777) can induce GLP-1 release, modulating insulin secretion and delaying gastric emptying