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doi: 10.3389/fendo.2025.1663499 Received 10 July 2025 Accepted 22 August 2025 Published 19 September 2025 Volume 16 - 2025 Edited by George Paltoglou, National and Kapodistrian University of Athens, Greece Reviewed by Fahad S

Consistent daily use over weeks or months is key for noticeable skin brightening and anti-aging effects

When you lose weight through any method, a portion of that weight comes from lean tissue (muscle and bone) rather than fat alone

However, medication should be paired with nutrition and lifestyle steps that improve insulin sensitivity, such as protein-forward meals, reduced ultra-processed food intake, strength training, walking after meals, sleep improvement, and stress reduction