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Research indicates that GHK-Cu can alter the activity of more than 4,000 human genes, shifting patterns away from inflammation and tissue degeneration toward profiles associated with repair, regeneration, and homeostasis [1]

Cheah CS, Yu FH, Westenbroek RE, Kalume FK, Oakley JC, Potter GB, et al

Gushen Jiedu capsule(GSJD)originated from the classic Chinese kidney tonic formula Shuilu Erxiandan in the Song Dynasty (1170 AD), which down-regulates pro-apoptotic protein Bcl-2-associated X protein (Bax) expression and up-regulates B cell lymphoma 2 (BCL-2) expression in the kidney of DN rats to regulate the mitochondrial apoptosis pathway

1995 Dec 29;771:240-51

It's addressing the metabolic dysfunction driving the oxidative load in the first place